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High in vivo pDNA Liver-Selective Transfection

DLin-KC2-DMA facilitates high in vivo pDNA liver-selective transfection in animal models possibly due to its head group pKa and lipid tail structure. This is a great article about how chemical structure affects delivery. Read about it here.

"In vivo delivery of plasmid DNA by lipid nanoparticles: the influence of ionizable cationic lipids on organ-selective gene expression"

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